Product Description
| Cat Number | HY-33299 |
|---|---|
| Category | Biochemical Assay Reagent |
| Pack Size | 1 EA |
| Description | Serpin B9-IN-1 (BTCA) is an inhibitor that specifically targets Serpin B9 ( SB9 ); SB9 is a natural inhibitor of granzyme B (GrB) , but may promote the metastasis of lung cancer cells into the bone marrow. SB9-overexpressing cancer cells promote proliferation and metastasis in an immune cell-dependent manner by binding to GrB. Inhibition of SB9 by Serpin B9-IN-1 significantly inhibits immunotherapy of lung cancer bone metastases in the caudal artery (CA) mouse model (LCBM) [1] . |
| Molecular Weight | 163.132 |
| Research Field | cancer |
| Purity | 98.0 |
| Formula | C8H5NO3 |
| Smiles | O=C(C1=CC=C2N=COC2=C1)O |
| Scientific Background | Others |
| Storage | -20°C, 3 years; 4°C, 2 years (Powder) |
| View Document | |
| Note | The product is for research use only |
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