Product Description
| Cat Number | HY-149132 |
|---|---|
| Category | Biochemical Assay Reagent |
| Pack Size | 1 EA |
| Description | Dendrogenin A (DDA) is a ligand for liver X receptor (LXR) , that induces the expression of sodium/iodine symporter, and increases iodine uptake. Dendrogenin A induces cell differentiation of MCF-7, and reactivates the function of lactating cells. Dendrogenin A induces the expressions of the TSH receptor, thyroid peroxidase, and thyroglobulin, and affects thyroid hormone generation. Dendrogenin A exhibits cytotoxicity in cancer cell B-CPAP and 8505c with IC 50 of 4.1 and 6.2 µM. Dendrogenin A arrests the cell cycle at G0/G1 phase [1] . |
| Molecular Weight | 513.80 |
| Research Field | Cancer |
| Formula | C32H55N3O2 |
| Smiles | C[C@@]12[C@]3([H])[C@](C[C@H]([C@]1(C[C@H](CC2)O)O)NCCC4=CN=CN4)([H])[C@@]5([H])[C@](CC3)([C@@](CC5)([H])[C@H](C)CCCC(C)C)C |
| Scientific Background | Metabolic Enzyme/Protease;Vitamin D Related/Nuclear Receptor |
| View Document | |
| Note | The product is for research use only |
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