Product Description
| Cat Number | HY-12495A |
|---|---|
| Category | Biochemical Assay Reagent |
| Pack Size | 1 EA |
| Description | ISRIB is a brain-penetrant inhibitor of integrated stress response (ISR) . Persistent activation of the ISR has been linked to the development of several neurological disorders as ISR represses translation through inhibiting eIF2B. ISRIB inhibits the ISR by promoting the nucleotide exchange activity of eIF2B and recovering the translation, and thus can be used for neurological disorders research [1] [2] [3] . |
| Molecular Weight | 451.34 |
| Research Field | Neurological Disease |
| Purity | 98.58 |
| Formula | C22H24Cl2N2O4 |
| Smiles | O=C(NC1CCC(NC(COC2=CC=C(Cl)C=C2)=O)CC1)COC3=CC=C(Cl)C=C3 |
| Scientific Background | Cell Cycle/DNA Damage;Others |
| Storage | -20°C, 3 years; 4°C, 2 years (Powder) |
| View Document | |
| Note | The product is for research use only |
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