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Ethidium homodimer

SKU: BTL-MCE-B-86228 | Brand: MedChem Express
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Product Description

Cat Number HY-D0093
Category Dye Reagent
Pack Size 1 EA
Description Ethidium homodimer (EthD-1) is a high-affinity fluorescent nucleic acid dye commonly used to stain mammals, bacteria, yeast, and fungi. Ethidium homodimer binds to DNA or RNA, enhancing fluorescence more than 30 times. The Ethidium homodimer has a strong positive charge, so it cannot cross cell membranes and stain living cells; But the Ethidium homodimer can cross the disordered region of the dead cell membrane to reach the nucleus and embed the DNA double strand to produce red fluorescence. Therefore, Ethidium homodimer is a relatively sensitive nucleic acid stain that can accurately detect nucleic acids in solution or in decomposing cells. Ethidium homodimer binds DNA, Ex/Em=528/617 nm [1] .
Molecular Weight 856.75
Research Field Others
Purity 99.0
Formula C46H50Cl4N8
Smiles NC1=CC=C2C(C(C3=CC=CC=C3)=[N+](CCCNCCNCCC[N+]4=C(C5=CC=CC=C5)C6=CC(N)=CC=C6C7=C4C=C(N)C=C7)C8=C2C=CC(N)=C8)=C1.Cl.Cl.[Cl-].[Cl-]
Scientific Background Cell Cycle/DNA Damage
Storage -20°C (Powder, sealed storage, away from moisture and light)
Pdf View Document
Note The product is for research use only
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