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IR-251

SKU: BTL-MCE-B-85977 | Brand: MedChem Express
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Product Description

Cat Number HY-155062
Category Dye Reagent
Pack Size 1 EA
Description IR-251 is a mitochondrion-targeting NIR fluorescent probe. IR-251 targets mitochondria via OATPs and causes mitochondrial damage in tumor cells. IR-251 IR-251 induced ROS overproduction by inhibiting PPARγ , and then inhibiting the β-catenin signaling pathway and downstream protein molecules related to the cell cycle and metastasis. IR-251 inhibits tumor proliferation and metastasis [1] .
Molecular Weight 886.48
Research Field Cancer
Formula C51H70BrClN4O2
Smiles CC1(C)C(/C=C/C2=C(Cl)/C(CCC2)=C/CC3N(CCCCCC(O/C(NC4CCCCC4)=N/C5CCCCC5)=O)C(C=CC=C6)=C6C3(C)C)=[N+](CC)C7=C1C=CC=C7.[Br-]
Scientific Background Cell Cycle/DNA Damage;Immunology/Inflammation;Metabolic Enzyme/Protease;NF-κB;Others;Stem Cell/Wnt;Vitamin D Related/Nuclear Receptor
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Note The product is for research use only
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