Product Description
| Cat Number | HY-150175 |
|---|---|
| Category | Dye Reagent |
| Pack Size | 1 EA |
| Description | HKSOX-1 and its derivatives (HKSOX-1r and HKSOX-1m) are novel fluorescent probes designed for highly sensitive and selective detection of the superoxide anion radical (O 2 •− ) in cellular environments. These probes utilize an aryl trifluoromethanesulfonate group that undergoes O 2 •− -mediated cleavage, releasing a free phenol and emitting fluorescence. They demonstrate excellent specificity and sensitivity across various pH ranges, withstand interference from strong oxidants and reductants typical in cellular contexts. HKSOX-1r, optimized for cellular retention, has been effectively employed in diverse assays including confocal imaging, flow cytometry, and zebrafish embryo studies, highlighting its utility in investigating O 2 •− roles in inflammation, mitochondrial stress, and other physiological processes [1] . |
| Molecular Weight | 712.40 |
| Research Field | Inflammation/Immunology |
| Formula | C23H6F10O11S2 |
| Smiles | O=C(C1=CC=C2C(C(OC23C4=CC(F)=C(C(F)=C4OC5=C(C(OS(=O)(C(F)(F)F)=O)=C(C=C53)F)F)OS(=O)(C(F)(F)F)=O)=O)=C1)O |
| Scientific Background | Others |
| View Document | |
| Note | The product is for research use only |
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