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4-Methylumbelliferyl-α-D-Glucopyranoside

SKU: BTL-MCE-B-85812 | Brand: MedChem Express
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Product Description

Cat Number HY-137873
Category Dye Reagent
Pack Size 1 EA
Description 4-Methylumbelliferyl-α-D-Glucopyranoside (4-Methylumbelliferyl-α-D-Glucose) is a fluorescent substrate for α-glucosidase , which releases the fluorescent moiety 4-methylumbelliferyl (4-MU) upon cleavage. 4-MU has pH-dependent fluorescence excitation activity, with excitation wavelengths of 320 nm at low pH (1.97-6.72) and 360 nm at high pH (7.12-10.3), respectively. The emission wavelength of 4-Methylumbelliferyl-α-D-Glucopyranoside increases with decreasing pH, ranging from 445-455 nm. 4-Methylumbelliferyl-α-D-Glucopyranoside can be used as a biomarker for Fabry and Pompe diseases to quantify α-glucosidase activity in infant blood spot samples.
Molecular Weight 338.31
Research Field others
Purity 99.99
Formula C16H18O8
Smiles O=C1C=C(C)C2=CC=C(O[C@@H]3[C@@H]([C@H]([C@@H]([C@@H](CO)O3)O)O)O)C=C2O1
Scientific Background Metabolic Enzyme/Protease;Others
Storage 4°C (Powder, stored under nitrogen)
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Note The product is for research use only
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