Product Description
| Cat Number | HY-133821 |
|---|---|
| Category | Dye Reagent |
| Pack Size | 1 EA |
| Description | N-Methylmesoporphyrin IX (NMM), a widely used G-quadruplex DNA specific fluorescent binder, is an efficient probe for monitoring Aβ fibrillation. N-Methylmesoporphyrin IX is an in situ inhibitor and an ex situ monitor for Aβ amyloidogenesis both in vitro and in cells. N-Methylmesoporphyrin IX is sensitive to G-quadruplexes DNA but has no response to duplexes, triplexes and single-stranded forms DNA. N-Methylmesoporphyrin IX is nonfluorescent alone or in monomeric Aβ environments, but emits strong fluorescence through stacking with the Aβ assemblies [1] . |
| Molecular Weight | 580.72 |
| Research Field | Neurological Disease |
| Purity | 97.69 |
| Formula | C35H40N4O4 |
| Smiles | O=C(O)CCC1=C2/C=C3C(CCC(O)=O)=C(C)C(/C=C(N/4C)/C(CC)=C(C)C4=C\C5=N/C(C(C)=C5CC)=C\C(N2)=C1C)=N/3 |
| Scientific Background | Cell Cycle/DNA Damage |
| Storage | -20°C (Powder, protect from light) |
| View Document | |
| Note | The product is for research use only |
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