Product Description
| Cat Number | HY-114491 |
|---|---|
| Category | Dye Reagent |
| Pack Size | 1 EA |
| Description | Rineterkib (compound B) is an orally available ERK1 and ERK2 inhibitor in the treatment of a proliferative disease characterized by activating mutations in the MAPK pathway. The activity is particularly related to the treatment of KRAS-mutant NSCLC, BRAF-mutant NSCLC, KRAS-mutant pancreatic cancer, KRAS-mutant colorectal cancer (CRC) and KRAS-mutant ovarian cancer. Rineterkib hydrochloride can also inhibit RAF [1] [2] . |
| Molecular Weight | 578.42 |
| Research Field | Cancer |
| Purity | 99.83 |
| Formula | C26H27BrF3N5O2 |
| Smiles | O=C(N[C@@H](C1=CC(F)=CC(Br)=C1)CNC)C2=CC=C(C3=NC([C@@H]4C[C@H](F)[C@@H](O)CC4)=CN=C3N)C=C2F |
| Scientific Background | MAPK/ERK Pathway;Stem Cell/Wnt |
| Storage | 4°C (Powder, sealed storage, away from moisture and light) |
| View Document | |
| Note | The product is for research use only |
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