Product Description
| Cat Number | HY-E70290 |
|---|---|
| Category | Enzyme |
| Pack Size | 1 EA |
| Description | N-Acetylgalactosaminyltransferase 1 (GALNT1) is a glycosyltransferase that initiates mucin-type O-glycosylation by transferring α-GalNAc from UDP-GalNAc to serine (Ser) or threonine (Thr) residues in proteins. Overexpression of N-Acetylgalactosaminyltransferase 1 in gastric cancer can promote abnormal O-glycosylation of CD44, thereby activating the Wnt/β-catenin signaling pathway and regulating the malignant behavior of gastric cancer cells. Additionally, N-Acetylgalactosaminyltransferase 1 plays a crucial role in cancer growth and metastasis by modifying the O-glycosylation of various glycoproteins, such as mucin (MUC1), osteopontin (OPN), matrix metalloproteinase-14 (MMP14), and integrin α3 [1] . |
| Molecular Weight | N/A |
| Research Field | Cancer |
| Formula | N/A |
| Smiles | [N-Acetylgalactosaminyltransferase 1] |
| Scientific Background | Metabolic Enzyme/Protease;Stem Cell/Wnt |
| Storage | Store at -20°C for 2 years |
| View Document | |
| Note | The product is for research use only |
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