Product Description
| Cat Number | HY-16700G |
|---|---|
| Category | GMP Small Molecule |
| Pack Size | 1 EA |
| Description | PNU-159682 GMP is a GMP grade PNU-159682 (HY-16700). PNU-159682, a metabolite of the anthracycline Nemorubicin, is a highly potent DNA topoisomerase II inhibitor with excellent cytotoxicity. PNU-159682 acts as a more potent and tolerated ADC cytotoxin than Doxorubicin for ADC synthesis. PNU-159682 can be used in EDV-nanocell technology to overcome agent resistance. |
| Molecular Weight | 641.62 |
| Research Field | Cancer |
| Formula | C32H35NO13 |
| Smiles | COC1=C(C(C(C(O)=C([C@@H](O[C@H]2C[C@H]3[C@H](O[C@H]4N3CCO[C@@H]4OC)[C@H](C)O2)C[C@@](C(CO)=O)(O)C5)C5=C6O)=C6C7=O)=O)C7=CC=C1 |
| Scientific Background | Antibody-drug Conjugate/ADC Related;Cell Cycle/DNA Damage |
| View Document | |
| Note | The product is for research use only |
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