Product Description
| Cat Number | HY-15794G |
|---|---|
| Category | GMP Small Molecule |
| Pack Size | 1 EA |
| Description | Nemorubicin (Methoxymorpholinyl doxorubicin) GMP is a GMP-class Nemorubicin (HY-15794). Nemorubicin is a Doxorubicin derivative with potent antitumor activity. Nemorubicin is highly cytotoxic to a variety of tumor cell lines presenting a multidrug-resistant phenotype. Nemorubicin not only intercalate into the duplex DNA, but also result in significant ligands for G-quadruplex DNA segments, stabilizing their structure. Nemorubicin requirs an intact nucleotide excision repair (NER) system to exert its activity [1] [2] [3] [4] . |
| Molecular Weight | 643.64 |
| Research Field | Cancer |
| Formula | C32H37NO13 |
| Smiles | COC1=C2C(C(C3=C(O)C(C[C@](C(CO)=O)(O)C[C@]4([H])O[C@H]5C[C@H](N6CCO[C@H](OC)C6)[C@H](O)[C@H](C)O5)=C4C(O)=C3C2=O)=O)=CC=C1 |
| Scientific Background | Cell Cycle/DNA Damage |
| View Document | |
| Note | The product is for research use only |
Share Item: