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MMAF (GMP)

SKU: BTL-MCE-B-84157 | Brand: MedChem Express
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Product Description

Cat Number HY-15579G
Category GMP Small Molecule
Pack Size 1 EA
Description MMAF (Monomethylauristatin F) GMP is a GMP grade MMAF (HY-15579). MMAF (Monomethylauristatin F) is a potent tubulin polymerization inhibitor and is used as a antitumor agent. MMAF (Monomethylauristatin F) is widely used as a cytotoxic component of antibody-drug conjugates ( ADC s) such as vorsetuzumab mafodotin and SGN-CD19A [1] [2] [3] .
Molecular Weight 731.96
Research Field Cancer
Formula C39H65N5O8
Smiles CC(C)[C@H](NC)C(N[C@H](C(N([C@@H]([C@@H](C)CC)[C@H](OC)CC(N1CCC[C@@]1([H])[C@H](OC)[C@@H](C)C(N[C@H](C(O)=O)CC2=CC=CC=C2)=O)=O)C)=O)C(C)C)=O
Scientific Background Antibody-drug Conjugate/ADC Related;Cell Cycle/DNA Damage;Cytoskeleton
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Note The product is for research use only
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