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MMAF (sodium) (GMP)

SKU: BTL-MCE-B-84156 | Brand: MedChem Express
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Product Description

Cat Number HY-15579BG
Category GMP Small Molecule
Pack Size 1 EA
Description MMAF sodium GMP is a GMP grade MMAF (sodium) (HY-15579B). MMAF sodium (Monomethylauristatin F sodium) is a potent tubulin polymerization inhibitor and is used as a antitumor agent. MMAF sodium (Monomethylauristatin F sodium) is widely used as a cytotoxic component of antibody-drug conjugates ( ADC s) such as Vorsetuzumab mafodotin and SGN-CD19A [1] [2] [3] .
Molecular Weight 753.94
Research Field Cancer
Formula C39H64N5NaO8
Smiles CC[C@H](C)[C@@H]([C@@H](CC(N1[C@@H](CCC1)[C@@H]([C@@H](C)C(N[C@H](C(O[Na])=O)CC2=CC=CC=C2)=O)OC)=O)OC)N(C([C@H](C(C)C)NC([C@H](C(C)C)NC)=O)=O)C
Scientific Background Antibody-drug Conjugate/ADC Related;Cell Cycle/DNA Damage;Cytoskeleton
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Note The product is for research use only
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