Product Description
| Cat Number | HY-15578G |
|---|---|
| Category | GMP Small Molecule |
| Pack Size | 1 EA |
| Description | McMMAF GMP is a GMP grade McMMAF (HY-15578). McMMAF is a protective group (maleimidocaproyl)-conjugated MMAF, which is a potent tubulin polymerization inhibitor. McMMAF can be used as a agent-linker for antibody-drug conjugates (ADC) . McMMAF is uncleavable, and must be internalized and degraded within a cell, releasing cysteine-McMMAF as the active agent [1] [2] . |
| Molecular Weight | 925.16 |
| Research Field | Cancer |
| Formula | C49H76N6O11 |
| Smiles | O=C([C@H](C)[C@H]([C@]1([H])CCCN1C(C[C@@H](OC)[C@@]([H])(N(C([C@H](C(C)C)NC([C@H](C(C)C)N(C)C(CCCCCN2C(C=CC2=O)=O)=O)=O)=O)C)[C@@H](C)CC)=O)OC)N[C@H](C(O)=O)CC3=CC=CC=C3 |
| Scientific Background | Antibody-drug Conjugate/ADC Related |
| View Document | |
| Note | The product is for research use only |
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