Product Description
| Cat Number | HY-110397G |
|---|---|
| Category | GMP Small Molecule |
| Pack Size | 1 EA |
| Description | KP-457 (GMP) is KP-457 (HY-110397) produced by using GMP guidelines. GMP small molecules work appropriately as an auxiliary reagent for cell therapy manufacture.KP-457 is a selective a disintegrin and metalloproteinase 17 ( ADAM17 ) inhibitor, with higher selectivity for ADAM17 than for other MMPs and ADAM10, and IC 50 s are 11.1 nM (ADAM17), 748 nM (ADAM10), 717 nM (MMP2), 9760 nM (MMP3), 2200 nM (MMP8), 5410 nM (MMP9), 930 nM (MMP13), 2140 nM (MMP14), and 7100 nM (MMP17), respectively [1] . |
| Molecular Weight | 480.55 |
| Research Field | Cardiovascular Disease |
| Formula | C21H24N2O7S2 |
| Smiles | CS(=O)(NCC1=CC=C(C(N(C=O)O)CS(=O)(C2=CC=C(OCC#CC)C=C2)=O)C=C1)=O |
| Scientific Background | Metabolic Enzyme/Protease |
| View Document | |
| Note | The product is for research use only |
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