Product Description
| Cat Number | HY-W757743 |
|---|---|
| Category | Isotope-Labeled Compounds |
| Pack Size | 1 EA |
| Description | Acalabrutinib-d 3 (ACP-196-d 3 ) is the deuterated form of Acalabrutinib (HY-17600). Acalabrutinib (ACP-196) is an orally active, irreversible, highly selective second-generation BTK inhibitor. Acalabrutinib covalently binds to Cys481 in the ATP-binding pocket of BTK. Acalabrutinib shows strong targeting and efficacy in mouse models of chronic lymphocytic leukemia (CLL). |
| Molecular Weight | 468.53 |
| Research Field | Others |
| Formula | C26H20D3N7O2 |
| Smiles | O=C(NC1=NC=CC=C1)C2=CC=C(C=C2)C3=C4C(N)=NC=CN4C([C@@H]5CCCN5C(C#CC([2H])([2H])[2H])=O)=N3 |
| Scientific Background | Others |
| View Document | |
| Note | The product is for research use only |
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