Product Description
| Cat Number | HY-W727879 |
|---|---|
| Category | Isotope-Labeled Compounds |
| Pack Size | 1 EA |
| Description | Upadacitinib- 15 N,d 2 (ABT-494- 15 N,d 2 ) is the deuterium-labeled Upadacitinib (HY-19569). Upadacitinib- 15 N,d 2 (ABT-494) is a potent, orally active and selective Janus kinase 1 ( JAK1 ) inhibitor ( IC 50 =43 nM). Upadacitinib- 15 N,d 2 (ABT-494) displays approximately 74 fold selective for JAK1 over JAK2 (200 nM) in cellular assays dependent on specific, relevant cytokines. Upadacitinib- 15 N,d 2 (ABT-494) can be used for several autoimmune disorders research [1] [2] . |
| Molecular Weight | 383.37 |
| Research Field | Others |
| Purity | 99.12 |
| Formula | C17H17D2F3N5 15NO |
| Smiles | CC[C@H]1[C@H](CN(C1)C([15NH]C([2H])([2H])C(F)(F)F)=O)C2=CN=C3C=NC(NC=C4)=C4N23 |
| Scientific Background | Others |
| Storage | -20°C, 3 years; 4°C, 2 years (Powder) |
| View Document | |
| Note | The product is for research use only |
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