Product Description
| Cat Number | HY-W654305 |
|---|---|
| Category | Isotope-Labeled Compounds |
| Pack Size | 1 EA |
| Description | Palbociclib-d 4 is deuterium labeled Palbociclib. Palbociclib (PD 0332991) is an orally active selective CDK4 and CDK6 inhibitor with IC 50 values of 11 and 16 nM, respectively. Palbociclib has potent anti-proliferative activity and induces cell cycle arrest in cancer cells, which can be used in the research of HR-positive and HER2-negative breast cancer and hepatocellular carcinoma [1] [3] [4] . |
| Molecular Weight | 451.56 |
| Research Field | Cancer |
| Formula | C24H25D4N7O2 |
| Smiles | O=C1C(C(C)=O)=C(C2=CN=C(N=C2N1C3CCCC3)NC4=NC=C(C=C4)N5CC([2H])(NC([2H])(C5)[2H])[2H])C |
| Scientific Background | Cell Cycle/DNA Damage;Others |
| View Document | |
| Note | The product is for research use only |
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