Product Description
| Cat Number | HY-W008719S |
|---|---|
| Category | Isotope-Labeled Compounds |
| Pack Size | 1 EA |
| Description | MPP+-d 3 (iodide) is deuterium labeled MPP+ (iodide). MPP+ iodide, a toxic metabolite of the neurotoxin MPTP, causes symptom of Parkinson's disease in animal models by selectively destroying dopaminergic neurons in substantia nigra. MPP+ iodide is taken up by the dopamine transporter into dopaminergic neurons where it exerts its neurotoxic action on mitochondria by affecting complex I of the respiratory chain. MPP+ iodide is also a high affinity substrate for the serotonin transporter (SERT)[1][2]. |
| Molecular Weight | 300.15 |
| Research Field | Neurological Disease |
| Purity | 99.60 |
| Formula | C12H9D3IN |
| Smiles | [2H]C([2H])([2H])[N+]1=CC=C(C2=CC=CC=C2)C=C1.[I-] |
| Scientific Background | Metabolic Enzyme/Protease |
| Storage | 4°C (Powder, protect from light) |
| View Document | |
| Note | The product is for research use only |
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