Product Description
| Cat Number | HY-N2037AS1 |
|---|---|
| Category | Isotope-Labeled Compounds |
| Pack Size | 1 EA |
| Description | Higenamine-d 4 -1 (Norcoclaurine-d 4 -1) hydrochloride is deuterium labeled Higenamine (hydrochloride). Higenamine hydrochloride is a selective LSD1 inhibitor ( IC 50 =1.47 μM) that can be isolated from aconite. Higenamine hydrochloride has anti-inflammatory and antibacterial activity. Higenamine (Norcoclaurine) can attenuate IL-1β-induced Apoptosis through ROS-mediated PI3K/Akt signaling pathway. Higenamine hydrochloride protects brain cells from oxygen deprivation. Higenamine can promote bone formation in osteoporosis through the SMAD2/3 pathway. Higenamine hydrochloride can be used to study cancer, inflammation, cardiorenal syndrome and other diseases [1] [2] [3] [4] [5] [6] [7] . |
| Molecular Weight | 311.80 |
| Research Field | Cancer;Infection;Endocrinology;Cardiovascular Disease |
| Formula | C16H14D4ClNO3 |
| Smiles | [2H]C(C([2H])=C(O)C([2H])=C1[2H])=C1CC2NCCC3=C2C=C(O)C(O)=C3.Cl |
| Scientific Background | Apoptosis;MAPK/ERK Pathway;Others;Protein Tyrosine Kinase/RTK |
| View Document | |
| Note | The product is for research use only |
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