Product Description
| Cat Number | HY-N0157S1 |
|---|---|
| Category | Isotope-Labeled Compounds |
| Pack Size | 1 EA |
| Description | Orotic acid- 13 C, 15 N 2 (monohydrate) is the 13 C and 15 N labeled Orotic acid[1]. Orotic acid (6-Carboxyuracil), a precursor in biosynthesis of pyrimidine nucleotides and RNA, is released from the mitochondrial dihydroorotate dehydrogenase (DHODH) for conversion to UMP by the cytoplasmic UMP synthase enzyme. Orotic acid is a marker for measurement in routine newborn screening for urea cycle disorders. Orotic acid can induce hepatic steatosis and hepatomegaly in rats[2][3][4]. |
| Molecular Weight | 177.09 |
| Research Field | Metabolic Disease |
| Purity | 99.93 |
| Formula | C4 13CH6 15N2O5 |
| Smiles | OC(C1=CC([15NH][13C]([15NH]1)=O)=O)=O.O |
| Scientific Background | Cell Cycle/DNA Damage;Metabolic Enzyme/Protease |
| Storage | 4°C (Powder, sealed storage, away from moisture) |
| View Document | |
| Note | The product is for research use only |
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