Product Description
| Cat Number | HY-I0678S |
|---|---|
| Category | Isotope-Labeled Compounds |
| Pack Size | 1 EA |
| Description | Regorafénib N-oxyde-d 3 (M2) is the deuterium labeled Regorafénib N-oxyde M2[1]. Regorafénib N-oxyde M2 is an active metabolite of Regorafenib. Regorafenib is a multi-target inhibitor for VEGFR1/2/3, PDGFRβ, Kit, RET and Raf-1 with IC50s of 13/4.2/46, 22, 7, 1.5 and 2.5 nM, respectively[2]. |
| Molecular Weight | 501.83 |
| Research Field | Cancer |
| Formula | C21H12D3ClF4N4O4 |
| Smiles | [2H]C([2H])([2H])NC(C1=CC(OC2=CC(F)=C(C=C2)NC(NC3=CC(C(F)(F)F)=C(C=C3)Cl)=O)=CC=[N+]1[O-])=O |
| Scientific Background | Metabolic Enzyme/Protease;Protein Tyrosine Kinase/RTK |
| View Document | |
| Note | The product is for research use only |
Share Item: