Product Description
| Cat Number | HY-G0021S1 |
|---|---|
| Category | Isotope-Labeled Compounds |
| Pack Size | 1 EA |
| Description | N-Desmethylclozapine-d 8 (hydrochloride) is the deuterium labeled N-Desmethylclozapine hydrochloride. N-Desmethylclozapine hydrochloride is a major active metabolite of the atypical antipsychotic agent Clozapine. N-Desmethylclozapine hydrochloride is a potent, allosteric and partial M1 receptors agonist (EC50=115 nM) and is able to potentiate hippocampal N-methyl-d-aspartate (NMDA) receptor currents through M1 receptor activation. N-Desmethylclozapine hydrochloride is also a δ-opioid agonist[1][2][3]. |
| Molecular Weight | 357.31 |
| Research Field | Infection |
| Purity | 99.74 |
| Formula | C17H10D8Cl2N4 |
| Smiles | ClC1=CC=C2NC3=CC=CC=C3C(N4C([2H])([2H])C([2H])([2H])NC([2H])([2H])C4([2H])[2H])=NC2=C1.[H]Cl |
| Scientific Background | Anti-infection;GPCR/G Protein;Metabolic Enzyme/Protease;Neuronal Signaling |
| Storage | -20°C, 3 years; 4°C, 2 years (Powder) |
| View Document | |
| Note | The product is for research use only |
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