Product Description
| Cat Number | HY-B0968S |
|---|---|
| Category | Isotope-Labeled Compounds |
| Pack Size | 1 EA |
| Description | Trimetazidine-d 8 (dihydrochloride) is the deuterium labeled Trimetazidine dihydrochloride. Trimetazidine dihydrochloride is a selective long chain 3-ketoyl coenzyme A thiolase inhibitor with an IC50 of 75 nM, which can inhibit β-oxidation of free fatty acid (FFA). Trimetazidine dihydrochloride is an effective antianginal agent and a cytoprotective agent, has anti-oxidant, anti-inflammatory, antinociceptive and gastroprotective properties. Trimetazidine dihydrochloride triggers autophagy. Trimetazidine dihydrochloride is also a 3-hydroxyacyl-CoA dehydrogenase (HADHA) inhibitor[1][2][3][4]. |
| Molecular Weight | 347.31 |
| Research Field | Cardiovascular Disease |
| Purity | 99.87 |
| Formula | C14H16D8Cl2N2O3 |
| Smiles | COC1=C(CN2C([2H])(C([2H])(NC([2H])(C2([2H])[2H])[2H])[2H])[2H])C=CC(OC)=C1OC.Cl.Cl |
| Scientific Background | Autophagy |
| Storage | 4°C (Powder, sealed storage, away from moisture) |
| View Document | |
| Note | The product is for research use only |
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